To identify molecules, scientists can use a type of biosensor called a nanopore -- a tiny hole in a membrane that allows fluid to flow through it. When a molecule of interest is driven into the pore, it partially blocks the flow of current, providing a signal researchers can use to identify the molecule. But in order to get a good measurement, the molecule must sit inside the pore for long enough. NIST researchers are using laser light to measure the energy of molecules as they transition into and out of nanopores. The resulting information can help scientists design optimized pores for detecting particular molecules.
