Studying sugars at the nanoscale

Animation explaining the glycocalyx, a sugar-rich layer on the surface of cells.
Client
Cornell University
Year
2019
Type
animation
Field
cell biology / glycobiology
Description
Animation explaining how sugars on cell surfaces affect cell signaling and cancer behavior.

Context

Matthew J. Paszek, Professor of Chemical and Biomolecular Engineering at Cornell University, studies the glycocalyx: the sugar-rich layer that covers cells.

His group found that in cancer cells the glycocalyx can expand dramatically, changing cell signaling and contributing to more aggressive cancers.

Approach

Cornell researchers provided video footage for the piece. I created the animation and edited the footage and rendered sections together so the video could move from research context to cell-scale and nanoscale explanation in one continuous narrative.

The animated sections use a soft, translucent 3D style to make the glycocalyx feel like a physical layer rather than an abstract label, connecting the visible cell surface to the molecular layer above it.